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ACS Webinars: Prodrug Strategies in Medicinal Chemistry
November 26 @ 2:00 pm - 3:00 pm
Join speaker Jarkko Rautio of the School of Pharmacy at University of Eastern Finland and moderator Victor Guarino of Bristol-Myers Squibb during this free interactive Tuesday broadcastas he demonstrates the versatility of prodrugs strategies in medicinal chemistry to overcome various ADMET barriers (absorption, distribution, metabolism, and excretion) with examples of successful prodrugs developed in industry and in academia.
What You Will Learn
• Why prodrug strategies are often invoked to overcome deficiencies in the physicochemical properties of a drug that limit formulation options
• Why prodrug modifications to improve physicochemical properties can also be used to overcome barriers for ADMET properties
• Why a decision to pursue a prodrug strategy should be done early because the development of a prodrug is usually more complex and less predictable in the clinic than that of other drugs