Organic solvents are integral to the way we do chemistry today, but they are also hazardous, and many are derived from non-renewable petroleum. Adapting reactions, workups, and isolations to aqueous conditions is a promising strategy for reducing our reliance on organic solvents.
Join 2020 Peter J. Dunn Award winner Dan Bailey of Takeda Pharmaceuticals as he discusses a process to manufacture an investigational drug substance almost entirely in water, including multiple controlled isolations from aqueous media. During this free interactive broadcast, you will learn how this water-based process uses 77% less material inputs, 94% less organic solvent, and surprisingly, 48% less water than the first-generation solvent-based process, while improving overall yield from 35% to 56% and reducing overall environmental, health, and safety impacts. This ACS Webinar is moderated by John Tucker of Neurocrine Biosciences and co-produced with the ACS Green Chemistry Institute.
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